Biomarker Testing

Right Treatment. Right Person. Right Time.

Every cancer is unique and advances in research provide the
opportunity to better understand your cancer and personalize
your treatment. Biomarker testing is one type of test that can
guide treatment decisions, but it’s important to ask your
healthcare team about biomarker testing BEFORE you begin
treatment.

What is biomarker testing?

A biomarker is a measurable trait that can give your
healthcare team a better understanding of your
health. Some biomarkers are simple measurements,
such as your heart rate or blood pressure. Other
biomarkers are measured through lab tests of your
blood, tissues and/or bodily fluids.

Cancer biomarkers are proteins, genes or other substances that are tested to better understand your cancer and provide more information that can help guide treatment decisions, including clinical trials. Biomarker testing may help determine your cancer subtype and/or whether certain treatments are more likely to work for your specific cancer. Biomarker testing can help predict the behavior of a cancer, the treatment response and chance of recovery. It can also be used to check the progress of treatment over time and whether the cancer is more likely to spread and/or if you’re at higher risk for certain cancer types. Biomarker testing is also known as comprehensive biomarker testing, molecular testing, tumor profiling, somatic testing, genomic testing and companion diagnostic testing.

What type of information will biomarker testing provide?

There are different cancer biomarkers for various types of cancer; although researchers have not yet identified
biomarkers for every cancer. There are 7 biomarker categories and test results can provide information about
the following:1

 

The National Cancer Institute has identified common cancer biomarkers here.

 

 

What questions should I ask my healthcare team?

Although biomarker testing is the standard of care for
some cancer types, your doctor may not bring it up prior
to treatment. Below you will find a few recommended
questions to ask your healthcare team.

Download

Before Testing
  • What type of biomarker testing is available for my type of cancer?
  • How will the test results affect my treatment options?
  • How is biomarker testing done? Will I need a biopsy? Do I need a blood test?
  • Will biomarker testing be covered by my insurance? If not, are there any financial assistance programs available to help cover the costs?
  • When will the test results be available?
  • How reliable is the test?
  • Who will explain the test results to me?
After Testing
  • What do the test results tell us about my specific cancer and the treatment options available?
  • Are there targeted therapies, immunotherapies, clinical trials or other treatments for this specific biomarker? Which options do you recommend for me? Why?
  • What are the risks/benefits of these options? You can find additional questions to ask about options under “Treatment Planning: Understanding Your Options”.
  • How do I obtain a copy of the test results?
  • Do I need any additional biomarker tests and/or other tests?
  • Is there any other information I should know?

 

 

For additional resources about biomarker
testing, please visit Health Match.

Genetics/Genomics
Genetics/Genomics

Right Treatment. Right Person. Right Time.

Every cancer is unique and advances in research provide the opportunity to better understand your cancer and personalize your treatment. Biomarker testing is one type of test that can guide treatment decisions, but it’s important to ask your healthcare team about biomarker testing BEFORE you begin treatment.

What is biomarker testing?

A biomarker is a measurable trait that can give your healthcare team a better understanding of your health. Some biomarkers are simple measurements, such as your heart rate or blood pressure. Other biomarkers are measured through lab tests of your blood, tissues and/or bodily fluids. Cancer biomarkers are proteins, genes or other substances that are tested to better understand your cancer and provide more information that can help guide treatment decisions, including clinical trials. Biomarker testing may help determine your cancer subtype and/or whether certain treatments are more likely to work for your specific cancer. Biomarker testing can help predict the behavior of a cancer, the treatment response and chance of recovery. It can also be used to check the progress of treatment over time and whether the cancer is more likely to spread and/or if you’re at higher risk for certain cancer types. Biomarker testing is also known as comprehensive biomarker testing, molecular testing, tumor profiling, somatic testing, genomic testing and companion diagnostic testing.

There are different cancer biomarkers for various types of cancer; although researchers have not yet identified biomarkers for every cancer. There are 7 biomarker categories and test results can provide information about the following:1

  • RiskShows the
    potential for
    developing a
    disease
  • DiagnosticDetects
    presence of a
    disease and/or
    identifies the
    subtype
  • MonitoringAssesses the
    status of a
    disease and
    effect of a drug
    or treatment
  • PrognosticIdentifies the
    chances of a
    disease occurring,
    recurring or
    progressing
  • PredictiveShows the
    likelihood you
    will respond to a
    particular
    treatment or
    drug
  • ResponseShows that you
    have reacted
    either positively
    or negatively to a
    treatment or drug
  • SafetyIndicates the
    likelihood,
    presence or extent
    of an adverse
    event to a
    treatment or drug

The National Cancer Institute has identified common cancer biomarkers here.

Although biomarker testing is the standard of care for some cancer types, your doctor may not bring it up prior to treatment. Below you will find a few recommended questions to ask your healthcare team.

Before Testing

  • What type of biomarker testing is available for my type of cancer?
  • How will the test results affect my treatment options?
  • How is biomarker testing done? Will I need a biopsy? Do I need a blood test?
  • Will biomarker testing be covered by my insurance? If not, are there any financial assistance programs available to help cover the costs?
  • When will the test results be available?
  • How reliable is the test?
  • Who will explain the test results to me?

After Testing

  • What do the test results tell us about my specific cancer and the treatment options available?
  • Are there targeted therapies, immunotherapies, clinical trials or other treatments for this specific biomarker? Which options do you recommend for me? Why?
  • What are the risks/benefits of these options? You can find additional questions to ask about options under “Treatment Planning: Understanding Your Options”.
  • How do I obtain a copy of the test results?
  • Do I need any additional biomarker tests and/or other tests?
  • Is there any other information I should know?

Download

For additional resources about biomarker
testing, please visit Health Match.

Genetics/Genomics
Genetics/Genomics